Best Medicine Episodes: Complete Season 1 & 2 Guide, Dates and Summaries

As of October 24, 2026, Best Medicine Episodes across two seasons on FOX. Season 1 has 13 episodes and concluded on April 7, 2026. Season 2 premiered on September 20, 2026, with five episodes released so far and 14 reportedly ordered. The next episode, “Can’t Stop the Healing,” is scheduled for Tuesday, November 3, 2026, at 8 p.m. ET.

Starring Josh Charles as Dr. Martin Best, the American medical comedy-drama follows a gifted but socially awkward former surgeon who leaves Boston for the small coastal town of Port Wenn, Maine. His blunt manner, fear of blood, and difficulty connecting with others lead to unusual medical cases and increasingly complicated personal relationships.

Best Medicine Season 1 Episodes: Complete List

Best Medicine Season 1 premiered on January 4, 2026, and ended on April 7, 2026, with 13 episodes.

The first season introduces Martin as he begins working as Port Wenn’s general practitioner. Despite his medical expertise, he struggles to win over residents who aren’t accustomed to his direct, sometimes abrasive approach.

The complete Season 1 episode guide includes the following original US air dates and storylines.

Ep.	Episode Title	Original Air Date	Episode Summary
1	Docked	Jan 4, 2026	Martin arrives in Port Wenn and clashes with locals while trying to conceal his blood phobia.
2	Bean There Done That	Jan 13, 2026	After diagnosing a potentially contagious illness, Martin cancels the town’s popular baked bean supper, upsetting residents.
3	Take Me Out of the Ballgame	Jan 20, 2026	Martin treats a high school baseball player whose injured arm may point to a more serious medical problem.
4	All the World’s Ablaze	Jan 27, 2026	A survival instructor goes missing, while Martin’s concerns about possible food poisoning anger townspeople.
5	Hello Darkness, My Port Wenn	Feb 3, 2026	Martin’s encounter with a reclusive patient contributes to a townwide power outage.
6	Eyewitness Blues	Feb 10, 2026	Martin investigates a man whose skin appears to have turned blue as Port Wenn prepares for its blueberry festival.
7	There Might Be Blood	Feb 17, 2026	A horror-themed town celebration tests Martin’s fear of blood when Louisa needs medical attention.
8	The Bogfather	Feb 24, 2026	The discovery of a body in a bog draws Martin into an unexpected murder investigation.
9	Doc Martin	Mar 3, 2026	Martin’s parents arrive without warning, bringing family tensions and concerns about his father’s health.
10	Port Wenn-ings and a Funeral	Mar 10, 2026	Martin treats an elderly patient experiencing hallucinations while dealing with personal complications.
11	Mind Your Own Buboes	Mar 24, 2026	A possible plague outbreak puts Port Wenn on alert as rumors about Martin and Louisa spread.
12	A Tale of Two Sister Cities	Mar 31, 2026	A Norwegian delegation visits town, and Louisa meets a specialist with ties to Martin’s past.
13	Norway No How	Apr 7, 2026	The finale brings revelations about Port Wenn’s sister-city arrangement, a challenging delivery, and developments in Martin’s personal life.

Throughout Season 1, Martin gradually establishes his medical practice while building uneasy relationships with Louisa Gavin, Aunt Sarah, and other residents. Those connections become more important in Season 2, particularly as his personal life grows harder to manage.

Best Medicine Season 2 Episodes: Released and Upcoming

Best Medicine Season 2 is still airing, picking up Martin’s story as he continues treating Port Wenn residents and navigating his relationships with Louisa and Eden.

The season reportedly has 14 episodes ordered, although only eight currently have published titles and US air dates. Five have aired, with three more scheduled.

Best Medicine Season 2 Episode List

The current Season 2 episode listings include the following released and upcoming installments.

Ep.	Episode Title	US Air Date	Summary / Status
1	Be Careful What You Fish For	Sep 20, 2026	A mysterious mermaid discovery stirs excitement in Port Wenn while Martin faces new medical and personal challenges. Aired
2	Breakin’ in Is Hard to Do	Sep 29, 2026	A pharmacy robbery involving Louisa’s medication leads Martin to investigate who might be responsible. Aired
3	Crate Expectations	Oct 6, 2026	Residents compete in the annual floating-crate race while Martin investigates three unusual positive pregnancy tests. Aired
4	No Place Like Om	Oct 13, 2026	Martin examines patients displaying strange symptoms after visiting a meditation retreat. Aired
5	Hare Today, Gone Tomorrow	Oct 20, 2026	Martin helps a grieving magician as unexpected developments complicate his relationships with Eden and Louisa. Aired
6	Can’t Stop the Healing	Nov 3, 2026	Martin investigates claims of miraculous healing while becoming increasingly aware of Louisa and Parker’s connection. Upcoming
7	Love Is a Battlefield	Nov 10, 2026	Plot details have not yet been confirmed. Upcoming
8	Back to the Suture	Nov 17, 2026	The episode is listed for this date, but its storyline remains unconfirmed. Upcoming

The November 3 broadcast of “Can’t Stop the Healing” is confirmed. Episodes listed for November 10 and November 17 remain subject to scheduling changes.

Although Season 2 reportedly has 14 episodes, titles and release dates for Episodes 9–14 have not been established. The available listings therefore represent the currently published schedule, not the complete season calendar.

Best Medicine Episode Release Schedule

New Best Medicine episodes generally air Tuesdays at 8 p.m. Eastern Time on FOX.

The series has made exceptions for its season premieres. Season 1 began on Sunday, January 4, 2026, while Season 2 opened on Sunday, September 20, 2026, before returning to the regular Tuesday slot.

The most recent episode, “Hare Today, Gone Tomorrow,” aired on October 20, 2026. No new installment is currently listed for October 27.

The next confirmed episode, “Can’t Stop the Healing,” airs November 3, from 8–9 p.m. ET/PT, according to FOX’s official episode announcement. Additional installments are listed for November 10 and November 17.

As with other network programs, these dates may change if FOX adjusts its schedule for special events or sports broadcasts.

Where to Watch Best Medicine Episodes

US viewers can watch Best Medicine through FOX broadcasts or stream available episodes through supported services.

FOX: New episodes air on the television network at their scheduled times. Live viewing depends on whether FOX is available through your local channels or television provider.

FOX One: Viewers can stream available Best Medicine episodes from both seasons through FOX’s streaming service. Subscription requirements and episode availability may vary.

Hulu: The series is also included in Hulu’s medical drama and comedy catalog. US subscribers can watch available episodes on demand, although newly broadcast installments may not appear immediately.

Watching through FOX’s live broadcast is different from streaming on demand. An episode’s television premiere doesn’t necessarily mean it becomes available across every streaming platform at the same time.

Outside the United States, streaming rights and release dates may differ. All episode dates in this guide refer to the original US broadcasts.

Should You Watch Best Medicine Episodes in Order?

It’s best to watch Best Medicine chronologically, starting with Season 1, Episode 1, “Docked.”

Many episodes revolve around medical cases that make sense on their own. However, the show also follows longer-running stories involving Martin’s blood phobia, his relationship with Louisa, and his often awkward interactions with Port Wenn residents.

Season 2 builds on those relationships rather than introducing an entirely separate storyline. Starting with Season 1 makes it easier to understand the characters’ changing dynamics and the personal conflicts that carry into later episodes.

New viewers should ideally finish all 13 episodes of Season 1 before beginning Season 2.

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